A study of analgesic effect of methylene blue injection in post conventional haemorrhoidectomy

Background: Haemorrhoids are common perianal disease. Milligan-Morgan haemorrhoidectomy operation is a classical haemorrhoid resection procedure that has been widely used as gold standard. Classical associated with considerable postoperative pain. This leads to patient discomfort; prolonged hospital stays and increased cost. The causes of post pain multifactorial. Methylene blue biological dye. It an inhibitor soluble guanylate cyclase. also found reduce cyclooxygenase products. mechanism action methylene likely be related the destruction dermal nerve endings.Methods: A prospective study 114 indoor patients was conducted compare effects 1% intradermal injection at local site paracetamol (I.V.) per requirement after admitted Surat municipal institute medical education research (SMIMER) Department General Surgery. Samples were divided into two groups each 57 patients, in case group given both groups’ requirement. Both assessed by visual analogue scale (VAS).Results: Present concluded mean post-operative score according (VAS) significantly lower compared control on 1st 3rd day.Conclusions: analgesic effect conventional without any significant side blue.